Meet Epicelline®, the Breakthrough Ingredient Behind the NIVEA Epigenetics Serum

Real progress in anti-aging comes from science that looks beyond quick, surface-level fixes. As innovation continues to shape the future of skincare, NIVEA has remained committed to research focused on long-term results. At the core of the new NIVEA Epigenetics Serum is Epicelline®, a breakthrough ingredient developed after extensive testing of more than 50,000 active ingredients and the evaluation of over 1,000 skin analyses. Backed by NIVEA’s patented Age Clock Technology, Epicelline® brings an epigenetics-led approach to anti-aging.

Epigenetics now plays a defining role in how we think about skin health. Epicelline® helps support the skin’s youthful functions while visibly addressing concerns such as wrinkles, loss of elasticity, and reduced firmness. Age Clock Technology is central here, drawing on epigenetic science to explore how lifestyle and environmental factors can influence the skin over time. Daily stressors such as sun exposure, sleep deprivation, and poor nutrition can disrupt these youth-preserving functions and accelerate the appearance of visible signs of aging. Epicelline® helps counter the impact of these factors, supporting skin in maintaining a more youthful-looking appearance.

Epicelline® goes beyond targeting the look of surface wrinkles. Powered by Age Clock Technology, it’s designed to support skin at a deeper level over time. With regular use, the NIVEA Epigenetics Serum has been shown to help reduce visible signs of skin aging in as little as two weeks*, leaving skin looking smoother, firmer, and more refreshed.

*Helps reduce visible signs of skin aging within two weeks. Independent study, 40 women, clinical and self-assessment scoring, 2024.